permaculture

[Lawrence London <lfljvenaura@gmail.com>]

Glyphosate, pathways to modern diseases II: Celiac sprue and gluten
intolerance
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945755/
Abstract

Celiac disease, and, more generally, gluten intolerance, is a growing
problem worldwide, but especially in North America and Europe, where an
estimated 5% of the population now suffers from it. Symptoms include
nausea, diarrhea, skin rashes, macrocytic anemia and depression. It is a
multifactorial disease associated with numerous nutritional deficiencies as
well as reproductive issues and increased risk to thyroid disease, kidney
failure and cancer. Here, we propose that glyphosate, the active ingredient
in the herbicide, Roundup®, is the most important causal factor in this
epidemic. Fish exposed to glyphosate develop digestive problems that are
reminiscent of celiac disease. Celiac disease is associated with imbalances
in gut bacteria that can be fully explained by the known effects of
glyphosate on gut bacteria. Characteristics of celiac disease point to
impairment in many cytochrome P450 enzymes, which are involved with
detoxifying environmental toxins, activating vitamin D3, catabolizing
vitamin A, and maintaining bile acid production and sulfate supplies to the
gut. Glyphosate is known to inhibit cytochrome P450 enzymes. Deficiencies
in iron, cobalt, molybdenum, copper and other rare metals associated with
celiac disease can be attributed to glyphosate's strong ability to chelate
these elements. Deficiencies in tryptophan, tyrosine, methionine and
selenomethionine associated with celiac disease match glyphosate's known
depletion of these amino acids. Celiac disease patients have an increased
risk to non-Hodgkin's lymphoma, which has also been implicated in
glyphosate exposure. Reproductive issues associated with celiac disease,
such as infertility, miscarriages, and birth defects, can also be explained
by glyphosate. Glyphosate residues in wheat and other crops are likely
increasing recently due to the growing practice of crop desiccation just
prior to the harvest. We argue that the practice of “ripening” sugar cane
with glyphosate may explain the recent surge in kidney failure among
agricultural workers in Central America. We conclude with a plea to
governments to reconsider policies regarding the safety of glyphosate
residues in foods.
*Keywords: *celiac disease, gluten, glyphosate, food, cytochrome P450,
deficiency