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  • From: "Tradingpost" <tradingpost@gilanet.com>
  • To: livingontheland@lists.ibiblio.org
  • Subject: [Livingontheland] Anti-cancer compound found in beans, nuts, cereals
  • Date: Thu, 15 Sep 2005 18:41:40 -0600

Anti-cancer compound found in beans, nuts, cereals
Thu Sep 15, 7:19 AM ET

LONDON (Reuters) - Eating a diet rich in beans, nuts and cereals could help

to prevent cancer because the foods contain a natural compound that
inhibits
the growth of tumors.

Scientists at University College London (UCL) said on Thursday that the
substance called inositol pentakisphosphate, which is also found in lentils

and peas, could also help researchers develop new therapies against the
disease.
"Our study suggests the importance of a diet enriched in foods such as
beans, nuts and cereals which could help prevent cancer," said Dr Marco
Falasca, of UCL's Sackler Institute, who reported the finding in the
journal
Cancer Research.

He and his team discovered that the compound inhibits an enzyme called
phosphoinositde 3-kinase which promotes tumor growth.

Scientists have been trying to develop drugs to inhibit the
cancer-promoting
enzyme but have had difficulty so far.

When the researchers tested inositol pentakisphosphate in mice and cancer
cells in the laboratory, it killed the animal tumors and enhanced the
effect
of drugs used against ovarian and lung cancer cells.

"Our work will now focus on establishing whether the phosphate inhibitor
can
be developed into an anti-cancer agent for human therapy," Falasca said in
a
statement.

The researchers believe the compound, which was non-toxic even at high
concentrations, could also be used to increase the effectiveness of
chemotherapy drugs.




  • [Livingontheland] Anti-cancer compound found in beans, nuts, cereals, Tradingpost, 09/15/2005

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